Versatile Xenopus tropicalis model with targeted integration of human BRAFV600E
Proceedings of the National Academy of Sciences, Volume 122, Issue 39, September 2025.
SignificanceGene knock-in animal models have been hindered by low efficiency. We addressed these limitations by leveraging the high fecundity ofXenopus tropicalisand its observable pigment phenotypes to construct a versatileBRAFV600E-targeted knock-in …
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